The sudden shutdown of millions of dollars in federal funding to Columbia University this month is already disrupting medical and scientific research at the school as it confronts a Friday deadline to bow to government demands for sweeping changes in how it deals with dissent on campus.

New York City-based Columbia University is taking initial steps to comply with federal directives to restore nearly $400 million in funding, more than half of which is tied to grants from the National Institutes of Health.

Deal with the loss of canceled federal contracts and grants over alleged antisemitism on campus or cave to Trump demands that have been criticized