It would seem that Sam McCall’s fate is sealed. Kelly Monaco has even finished working at General Hospital. Rumors have started swirling that Cyrus Renault kills her character by injecting digitalis into her IV after she undergoes surgery to donate part of her liver to boyfriend Dante Falconeri’s comatose former wife,

Sam McCall has been a staple on General Hospital ever since her character arrived in 2003. Kelly Monaco joined the show after the cancellation of Port Charles, the GH spinoff. While she played Livvie Locke on Port Charles, Sam McCall was a new character created for General Hospital.

Longtime General Hospital star Kelly Monaco is opening up about her exit from the ABC soap. After 21 years on the sudser and two Daytime Emmy nominations for her work within the Port Charles universe, Monaco wrote on Instagram, “Last scene with the Davis girls. 😘🥲🙏🏻 still doesn’t make any sense to me.”

After Kelly Monaco was fired from "General Hospital," the Emmy-nominated actor's mother, Carmina, took to Instagram to share her reaction to the news.

General Hospital viewers were shocked to learn Kelly Monaco (Sam) had been fired. As the storyline for Sam’s death plays out, her fan base is making noise and being heard. There is plenty of chatter about the writers using Sam’s death to prop up the return of Lulu (Alexa Havins).