The Jacksonville Jaguars (4-12) are 4.5-point underdogs in a road AFC South matchup against the Indianapolis Colts (7-9) on Sunday, January 5, 2025 at Lucas Oil Stadium.NFL odds courtesy of BetMGM

Mac Jones and the Jacksonville Jaguars (4-12) are in Indianapolis to face Joe Flacco and the Colts (7-9). This is a game with zero playoff implications but is one whose result carries massive draft ramifications especially for Jacksonville as nine teams are within one game of the first nine slots in the upcoming NFL Draft.

As it stands, Jacksonville holds 10 picks in the 2025 NFL Draft. They’re slated to pick once in the first round, once in the second round, twice in the third and fourth round, once in the fifth round, twice in the sixth round and once in the seventh round.

The Indianapolis Colts and Jacksonville Jaguars find themselves in similar predicaments Sunday. Neither will be playing again after Week 18.

The Jacksonville Jaguars sit at No. 5 in the current NFL draft order. If that's where they stay after Week 18, here's who mock drafts have them taking.

Strangely, vibes are much better on the sidelines of the 4-12 team than the one at 7-9. While a loss is better for the Jaguars' chances at getting a top-five pick — even the first pick is still an outside shot — they are not playing with that mentality. Even if the Colts sneak out a victory here, it will not be by more than five points.

The Indianapolis Colts and Jacksonville Jaguars complete disappointing seasons at Lucas Oil Stadium. Who ya got?

Preview the Week 18 matchup between the Indianapolis Colts and Jacksonville Jaguars with predictions, odds, over/under, spread, betting lines and more.