The road ahead for the San Francisco 49ers in 2025 could be incredibly smooth. With the opponents they are set to face, they ...

In the final game of Week 17, the San Francisco 49ers will play host to the Detroit Lions on "Monday Night Football." San ...

SportsLine's model has simulated San Francisco vs. Detroit on Monday Night Football 10,000 times and revealed its MNF picks ...

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota ...

Detroit Lions offensive tackle Penei Sewell has been selected to his third consecutive NFC Pro Bowl roster, but the former Oregon Ducks unanimous All-American s ...

The Detroit Lions continue to set franchise and league marks across the board. Their latest re-writing of the NFL history ...

Follow live coverage as Minnesota and Detroit, both with 14-2 records, square off with the NFC's top seed and a bye in the ...

The NFL Week 17 schedule concludes with a pair of high-profile NFC teams on Monday Night Football. The Detroit Lions at San ...

The 49ers have nothing to play for other than pride at this point. They're facing a Lions team that has the best record in ...

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

With injuries left and right, the Lions’ pass defense has been flimsy of late heading into Sunday night’s battle for the No.