The Sackler family agreed to give up ownership of the company that manufactures the powerful opioid. A previous deal was rejected by the Supreme Court.

The deal comes after the Supreme Court blocked a controversial bankruptcy plan for Purdue that shielded Sackler family members from future lawsuits.

The settlement is the largest deal to date with the people primarily who played an “instrumental role” in driving the opioid crisis, according to the office of Massachusetts Attorney General Andrea Joy Campbell.