The 49ers start Thanksgiving week with a pilgrimage to Lambeau Field, where their last visit was a snow-topped upset of the No. 1-seed Packers in the 2021 season’s divisional playoffs.

San Francisco 49ers wide receiver Brandon Aiyuk is widely expected to start the 2025 season on the physically unable to ...

Each week we’ll set the stage for the 49ers’ upcoming game, and here is what to come in Week 1 for Sunday’s season opener at Pittsburgh.

This is the live blog for the San Francisco 49ers' Week 1 Monday night home game against the New York Jets. I will update this frequently with information and analysis from the press box.

PITTSBURGH -- This is the live blog for the San Francisco 49ers' Week 1 road game against the Pittsburgh Steelers. I will update this with information and analysis from the press box.

The 49ers' offensive line was a big-time question mark entering the year. They looked like they had an opportunity to improve this season, but they surpassed expectations in Week 1.

The NFL season is still nearly two months away, but a handful of bets for Week 1 are already gaining traction among fans.

The San Fransisco 49ers will be looking to put the bad injury luck from last year’s NFC Championship game behind them and start their 2023 campaign strong with a Week 1 visit to Pittsburgh for a ...

After a 23-yard pass from Garoppolo to George Kittle brought the 49ers to the Detroit 16, Lance entered for a 1-yard quarterback keeper. Advertisement Three plays later, he was back.

Time will tell on that one, but I don’t think the 49ers are feeling some false euphoria here. They’re feeling a bit of real euphoria after so much could’ve been lost this summer. While Kyle ...