AML represents a disease that develops from the uncontrolled growth and survival of undifferentiated leukemia stem cells. These stem cells are particularly dependent for survival upon the MCL-1 ...

These patients were enrolled in the files of the Institute of Pathology, Charité ... derivation and frequency of altered niche cells in the AML BM microenvironment.

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells. Its diversity stems from numerous genetic ...

acute promyelocytic leukemia (APL or M3-AML). These patients are prone to life-threatening hemorrhages following chemotherapy due to cell lysis and release of procoagulants from the leukemic cells.

The rate of cGVHD-free survival was 78% at 1 year in patients who received Orca-T compared with 38% among patients who ...

Increased mixed chimerism, as detected by AlloHeme, could predict post-transplant relapse “with a high degree of accuracy,” said Monzr M. Al Malki, MD.

MPN and AML) and she has developed research expertise in biomarker and mutation profiling of cancers with cross correlation of clinical and pathology data (including histology, immunohistochemistry, ...