A recent study by a team from Chiba University has demonstrated a promising approach for fighting antibiotic resistance by identifying a compound, V-161, that inhibits a sodium-pumping enzyme critical ...

PAGE Therapeutics, a biotech company focused on tackling metastatic cancer spread at its root, is pleased to announce the ...

The prize was for the determination of the detailed mechanism by which ATP shuttles energy. The enzyme which makes ATP is called ATP synthase, or ATPase, and sits on the mitochondria in animal cells ...

In the next step, the researchers want to develop new molecules based on digoxin that are even better at dissolving the CTC clusters.

Nonetheless, all remodelers contain a subunit with a conserved ATPase domain. In addition to the conserved ATPase, each remodeler complex also possesses unique proteins that specialize it for its ...

TFEB targets only the aberrant tau species and this specificity may be conferred by a unique tau-induced V-ATPase-mediated TFEB stress sensing and signaling program. This project is to determine TFEB ...

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly ...

The present clinical study, published in the top-tier scientific journal Nature Medicine (link), has shown for the first time ...