Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists. The findings ...

A third autotrophic pathway (Wood–Ljungdahl pathway) uses a reductive acetyl-CoA pathway and is only found in strictly anaerobic bacteria and archaea. A fourth pathway uses the 3 ...

Here the authors investigate the regulatory mechanisms of acetyl-CoA (Ac-CoA) biosynthesis in Bacillus subtilis, probing the interaction between acetyl-CoA synthetase (AcsA) and acetyltransferase ...