UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

Adenine and guanine are double-ring molecules called purines, but cytosine, thymine and uracil are all pyrimidines: single rings. To maintain its orderly structure, single rings on one strand can ...

How can just four nitrogenous bases--adenine, cytosine, guanine, and uracil--possibly code for all 20 amino acids? Thus, early researchers quickly determined that the smallest combination of As ...

Other combinations of the atoms form the four bases: thymine (T), adenine (A), cytosine (C), and guanine (G). These bases are the rungs of the DNA ladder. (It takes two bases to form a rung -- one ...

The purine structure consists of a pyrimidine ring (positions 1 to 6) fused to an imidazole ring (positions 7 to 9). Adenine and guanine, the two most common purines in DNA and RNA, share this core ...

Traits as diverse as the color of a person's eyes and the scent of a rose are determined by the information contained in DNA. Learn how this information is coded by strings of molecules called ...

The thymine-adenine (T-A) base pair is held together by fewer hydrogen bonds compared to the guanine-cytosine (G-C) base pair, which has three hydrogen bonds. The complementary base pairing in DNA ...

RNA is formed by linking molecules of ribose (a monosaccharide) with phosphate groups that bind to four types of nitrogenous ...

The authors have demonstrated the use of adenine base editors delivered via adeno-associated viruses to introduce edits in the mitochondrial genome. The manuscript describes the methodology well, and ...