A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and ...

Therapeutic efforts in acute myeloid leukemia (AML ... Researchers identified 55 distinct hematopoietic cell states across the dataset. All leukemia cells were projected onto these reference ...

An international study led by the University of Colorado Cancer Center has uncovered why a widely used treatment for acute ...

AML: Acute myeloid leukemia ... population of cells, termed leukemic stem cells (LSCs) or leukemia-initiating cells, which are capable of self-renewal, proliferation and differentiation into ...

Given that not all ... differentiation anomalies. Using bulk RNA sequencing data from more than 1,200 AML patient samples, the Toronto team estimated the abundance of each leukemia cell state ...

Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. AML usually begins in cells ...

An international study led by the University of Colorado Cancer Center has uncovered why a widely used treatment for acute myeloid leukemia (AML) doesn’t work for everyone. The findings could help ...

Despite advances in cancer treatment in recent years, five-year survival rates for acute myeloid leukemia (AML ... is known to impair the differentiation of myeloid cells, which leads to ...

Chronic myeloid leukemia (CML) is highly treatable ... In people with CML, something goes wrong with a type of blood stem cell called a myeloid cells. Instead of maturing into fully functioning ...

Among patients with acute myeloid leukemia (AML) in remission following second-line salvage therapy, the immunotherapeutic agent galinpepimut-S (GPS) demonstrated preliminary signals of efficacy and ...