8 were successful, although the activity of the selected ribozyme (which they designate as AD02) was low: less than 5% of the input tRNA was aminoacylated. This yield corresponded to 0.4 ...

Some vtRNAs are aminoacylated by host tRNA synthetases, suggesting that they may be bona fide translational components. Moreover, aberrantly processed or modified tRNAs are targets for nuclease ...