During that same year, Marshall Nirenberg and Heinrich Matthaei began deciphering the genetic code, and they determined that the codon UUU specifically represented the amino acid phenylalanine.

Hence, the resulting products provided clues that the researchers could use to deduce potential codon–amino acid relationships. For example, when A and C were mixed with polynucleotide ...

The rules for wobble base pairing are as follows: The first two bases of a codon always form standard Watson-Crick base pairs with the corresponding bases of the anticodon (A-U, G-C). The third base ...