Hence, the resulting products provided clues that the researchers could use to deduce potential codon–amino acid relationships. For example, when A and C were mixed with polynucleotide ...

Following this discovery, Nirenberg, Philip Leder, and Gobind Khorana identified the rest of the genetic code and fully described each three-letter codon and its corresponding amino acid.

The rules for wobble base pairing are as follows: The first two bases of a codon always form standard Watson-Crick base pairs with the corresponding bases of the anticodon (A-U, G-C). The third base ...