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Reprogramming Liver Immunity: A Lipid Nanoparticle Approach for Pancreatic Cancer Therapy
A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...
Hosted on MSN1mon
β-glucans show promise as adjuvants for allergy treatment
CD80, CD86 and MHCII to varying degrees. Another finding: the cytokine secretion induced by β-glucans was partly dependent on the activation of the intracellular Dectin-1 adapter molecule Syk.
The Scientist13y
Top 7 in immunology
In addition to binding the CD80 and CD86 receptors on the surface of antigen presenting cells, impairing their ability to activate T cells, the CTLA-4 receptor on T helper cells can physically snatch ...
Nature1mon
A major susceptibility locus for atopic dermatitis maps to chromosome 3q21
Genes encoding two type-I membrane proteins of the immunoglobulin superfamily, CD80 and CD86 antigens, have been mapped to this region. Both CD80 and CD86 interact with CD28 to provide ...