They found that deficiencies in an enzyme called catalase-peroxidase, encoded by a gene called katG, make drug-resistant TB more susceptible to bedaquiline. Mutations in katG are the most common ...
Enzymatic antioxidants—including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GRd), and thioredoxin reductase—play crucial roles in ...
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