The resulting chimera mouse confirms that single-celled organisms had the biolgical tools to develop specialized cells before the creation of stem cells and the entire animal kingdom. What’s the ...

A chimera is an organism with two different genetic ... Cancer Center successfully implanted human stem cells into a mouse embryo. The mouse had 4% human cells, the highest percentage ever achieved.

Jian Feng studies mouse-human chimeric embryos with the goal of building better models of Parkinson’s disease. CREDIT: SANDRA KICMAN Eventually, Feng wants to use chimera technology to create better ...

For example, scientists recently reported the successful growth of mouse pancreases inside of rats. The ultimate goal of this type of work is to grow human organs inside of other animals as a ...

Knockout and knock-in mouse lines can be generated using gene targeting in embryonic stem cells with chimera production or CRISPR genome editing in mouse zygotes. For projects involving CRISPR genome ...