is associated with an abnormal phenotype (the central two are normal chromosome 15). d) The inv dup (22) (right) is associated with the cat eye syndrome.

For instance, deletions that span a centromere result in an acentric chromosome that will most likely be lost during cell division. As with duplications, deletions can affect gene dosage and thus ...

Scott W. Stuart, MD, MS; Casey H. King, BA; G. Shashidar Pai, MD Such observations emphasize the importance of clarifying the origin of a genetic variation by studying the parents for comparison ...

Scott W. Stuart, MD, MS, Fellow, Developmental Pediatrics Medical University of South Carolina, Children's Hospital, Charleston, South Carolina Casey H. King, BA ...