For instance, deletions that span a centromere result in an acentric chromosome that will most ... Also, the larger the deletion, the more genes are likely to be involved, and the more drastic ...

Of these, five showed that the rearranged chromosome was of paternal origin ... in these patients were contained within the common SMS deletion, suggesting involvement of the same genomic region ...

This reshuffling usually disrupts the normal function of genes in the chromosome ... 5, 7, 9 and 18. The case reported in the current study is the first 5q14.3 microdeletion syndrome due to ...