In addition to CYP11B2, cells later in the cell-fate pathway also expressed more CYP17A1, which contributes to cortisol ...
The actions of the cortisol-synthesis inhibitors must be considered in the context of the metabolic pathways involved in steroid biosynthesis (Fig. 1). Metyrapone decreases cortisol production ...
Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and ...
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