This three-step pathway involves the enzymes carboxylesterase, cytidine deaminase and thymidine phosphorylase (Figure 1), all of which are expressed in hepatic and tumor tissue. In particular the ...

including one called '23C9' that we later designated 'activation-induced cytidine deaminase' (AID). Additional cDNA molecules encoding proteins known to be induced by cytokine stimulation ...

Activation-induced cytidine deaminase (AID) modifies the nucleotide cytidine, thereby initiating strand breaks in immunoglobulin DNA that promote antibody diversity. Polyxeni Gourzi et al.