In all these pathways, special proteins detect changes in the DNA and repair them. This machinery is also responsible for ...

The first four disorders seem to result from defects in the excision repair pathway ... a link with DNA repair defects will be mentioned here. Oxidative stress and DNA damage are also implicated ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, ...

The three-year study included Colgate alumni Elisabeth Pezzuto ’22, Patrick Wertimer ’23, Aidan Conroy ’23, Maxwell ...

The importance of understanding DNA repair Our cells protect their DNA by constantly monitoring and repairing any damage. When DNA is damaged, internal signals activate within the cell to pinpoint ...

Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new ...

internal signals activate within the cell to pinpoint the damage and recruit specialised proteins-DNA repair "machines"-to fix the break. This repair process must be tightly regulated to ensure ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often ...

Metabolic liver disease might not get as much attention as heart disease or diabetes, but it affects around one in four ...

In this Review, familial and sporadic neurological disorders reported to have an etiological link with DNA repair defects are discussed, with special emphasis placed on the molecular link between ...