Thus, viral ATP-dependent DNA ligases have an intrinsic nick-sensing function. Nick recognition by vaccinia DNA ligase and Chlorella virus DNA ligase also depends on occupancy of the AMP binding ...

This article was originally published with the title “ The Recognition of DNA in Bacteria ” in Scientific American Magazine Vol. 222 No. 1 (January 1970), p. 88 doi:10.1038 ...

"In simple type II R-M systems, methylase and restrictase are two separate proteins, whereas in BREX, both the methylation of its own DNA and the recognition and restriction of unmethylated viral ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that comprise the human genome. But where and how does the famous double helix fit into ...

While these enzymes allow large DNA insertions, they only recognize specific recombinase recognition sites. “These recombinase recognition sites rarely occur in nature where we want to insert ...

He predicted that the restriction enzyme and the modification enzyme act on the same DNA sequence, called a recognition sequence. In this way, the bacterial cell's own self-defense mechanism ...

Scientists used the restriction enzymes to, among other things, cut DNA at particular locations and insert new genes at the cutting sites. However, it is difficult to determine in advance exactly ...