Focusing on the schematic illustration in a, two DNA ... the replication fork. The helicase exposes the bases of the DNA helix for the leading-strand polymerase to copy. DNA topoisomerase enzymes ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

For the first time, Professor Veyrier and his team at INRS have discovered a family of enzymes that can cut specific sequences in single-stranded DNA. These enzymes, called site-specific ...

A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Today, scientists recognize three categories of restriction enzymes: type I, which recognize specific DNA sequences but make their cut at seemingly random sites that can be as far as 1,000 base ...

such as cell replication or repair. Single-stranded DNA is also used in many technologies (sequencing, gene editing, molecular diagnostics, nanotechnology). To date, no endonuclease – enzyme that cuts ...

An INRS research team has identified a new family of enzymes that can make precise cuts in single-stranded DNA. A few years ago, the introduction of CRISPR technology marked a significant breakthrough ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement. A new paper showcases the power of scalable protein ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...