Dengue virus infects about 400 million people annually around the world, ... mutations in the virus' E protein causes its transformation into bumpy particles.

A dengue virus protein alters the blood vessel surface and makes it leaky. PLOS. Journal PLOS Pathogens DOI 10.1371/journal.ppat.1005738 ...

We have determined the crystal structure of a recombinant protein in which the dengue virus prM is linked to the envelope glycoprotein E. The structure represents the prM-E heterodimer and fits well ...

A soluble version of the E protein, called sRecE, can form the same homodimer structure observed by E proteins on the surface of the virus. Dengue- and Zika-infected patients develop neutralizing ...

Immature dengue virus particles undergo a dramatic conformational change upon exposure to the acidic environment of the late secretory pathway. The interactions of the E fusion proteins and prM ...

A major route toward creating effective vaccines against dengue virus and Zika involves the E protein that covers the surface of each viral particle. If we could develop strong antibodies against ...