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When a cell divides, the genome has to be duplicated, then the two copies separated and one goes to each daughter cell. But ...
Researchers have identified mutations in the non-coding gene RNU2-2 as a cause of a newly defined neurodevelopmental disorder ...
City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.
In a manuscript published today in the American Journal of Psychiatry titled "Long-Read Genome Sequencing in Clinical ...
Investigators have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as ...
A seminal study by researchers at the Icahn School of Medicine at Mount Sinai and their collaborators in the United Kingdom, ...
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Gene 'silencer' in junk DNA prevents fatal neurological diseasePeople with ADLD have a duplication of the lamin B1 gene without the silencer—and that results in demyelination and disease symptoms. But an unknown number of people who have the mutation that ...
Scientists have now found that donating blood may stimulate beneficial genetic changes. Frequent blood donors were found to carry mutations in blood stem cells that boosted the growth of healthy new ...
Researchers have identified a new molecular target for treating pancreatic cancer. Scientists focused on transcription-replication conflicts (TRCs), which occur when the mechanisms responsible for ...
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