Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.

and lower thoracic esophagus in 19 lesions. The median size of the lesions was 20 mm (range 2–74 mm) (Table 1). Of the 68 lesions, 32 were classified in the brownish epithelium group ...

Acid reflux leads to inflammation and mucosal damage, resulting in the change of microbiome in the distal esophagus. This process allows the columnar epithelium to replace the original squamous ...

Endoscopic submucosal dissection (ESD) can remove large esophageal lesions in one procedure, but epithelial loss creates an ulcer. Ulcer healing can cause esophageal scarring and stenosis ...