When an estrogen molecule binds to an estrogen receptor (ER), the receptor dissociates from its cytoplasmic chaperones, the receptor-associated proteins.

Estradiol is the most potent form of estrogen. Now, researchers have developed a way to monitor estradiol levels by detecting it in sweat. Estradiol plays a major role in female health and fertility; ...

The therapeutic landscape for hormone receptor-positive (HR+) advanced breast cancer (BC) is moving from generalized ...

The sequential recruitment of coactivators to the estrogen receptor complex results in dynamic specific structural and functional changes that ... Molecular Cell, 2017; DOI: 10.1016/j.molcel.2017. ...