Recent research has focused on the unique characteristics and functions of eukaryotic translation initiation factors, particularly eIF4G and eIF4A, in these organisms. This research is essential ...

Eukaryotic translation initiation factors, particularly eIF4E, play a crucial role in the regulation of protein synthesis, which is often dysregulated in cancer. Recent research has focused on ...

The Merrick laboratory seeks to identify all of the eukaryotic translation initiation factors and determine their sequential utilization in the initiation pathway. A secondary goal is to characterize ...

The extent of human eukaryotic translation initiation factor eIF3 interaction with the 3' ends of mRNA 3' untranslated regions (3'-UTRs) correlates with the level of translation.

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...