Jassey, DO Fifth disease, or erythema infectiosum, is a contagious viral infection best known for causing a blotchy red rash ...

Fifth disease – so called because it was the fifth red-rash childhood disease to be identified – is generally a mild illness that most commonly affects preschool and school-age children.

It is rarely serious, however, and usually resolves without complications. Fifth disease is a viral rash that is common in children. Doctors sometimes call it erythema infectiosum. This rash often ...

What it looks like: Fifth Disease is caused by Parvovirus B19 and presents with a red rash on the cheeks, arms, and legs that can last for several weeks. This condition occurs most often in children.