In this article, Sartorius discusses how their iQue® product can be used to examine donor and antibody diversity in NK cell-mediated ADCC through the use of multiplex assays and flow cytometry.

This eBook highlights some of the most recent advancements in the field of antibody discovery, covering a range of methods of antibody characterization and the novel modalities produced.

Accelerating antibody discovery using advanced flow cytometry The past decade has seen an explosion in the number of antibody-based therapeutics on the market. A huge driver of this has been the ...

After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to master is antibody panel design. Optimizing a multicolor ...

Flow cytometry relies on a combination of fluorophores and antibodies as detection reagents. Fluorophores can absorb and emit specific wavelengths of light from a wide range, depending on the ...

Multiplexed, multiparameter screening assays are foundational to the drug discovery process. By collecting more information, more rapidly – whether the focus antibodies, small molecules, or phenotypic ...

Here, binding of antibodies from various body fluids to pure-cultured live bacteria is made visible with fluorophore-conjugated secondary antibodies and measured by flow cytometry.

Mass cytometry dramatically enhances the dimensionality of fluorescence-based flow cytometry for phenotypic analysis of heterogeneous cell populations.

This article explores common challenges faced by flow cytometry users, such as fluorochrome selection, the utility of tandem dyes and managing spectral overlap, to help optimize your panel design for ...