Background: Although intrapartum antimicrobial prophylaxis has lowered the incidence of early onset group B Streptococcus (GBS) sepsis, there are concerns that the increased use of antibiotics may ...

Currently antibiotic prophylaxis administered to a woman during labour is the main means of preventing GBS disease in newborn infants, but only if the bacterium is detected during pregnancy.

Gestation at <37 weeks, duration of membrane rupture of ≥18 hours, or temperature of ≥100.4 ºF (≥38.0 ºC) are clinical indications for intrapartum prophylaxis if the GBS status is unknown ...