With MeiraGTx eyeing up how to take the drug through phase 3 and onto commercialization, Hologen has stepped in. The ...

Dysbiosis refers to an imbalance of microorganisms in the gut microbiota, which can lead to a wide range of health problems.

GAD is needed to make GABA, a chemical messenger that helps tamp down neuron activity. Without it, the brain fires off signals at an excessive rate, leading to the muscle cramps and stiffness seen ...

The venture aims to advance MeiraGTx’s Parkinson’s gene therapy through Phase III trials with up to $430m in funding from ...

ENX-102 is a highly specific GABA A α 2,3,5-positive allosteric modulator that is in development for the treatment of generalized anxiety disorder (GAD). Based on robust preclinical data and a ...

It was imperative that these compounds did not inhibit L-glutamic acid decarboxylase (GAD) too, an enzyme that converts L-glutamate into GABA. So, in 1989, Ryszard Andruszkiewicz, a scholar ...