Gene duplication provides raw material for functional ... novelty is built on a conserved enzymatic mechanism. The IAD model provides a general mechanism for the evolution of new protein functions ...

The “Innovation-Amplification-Divergence” model posits that novel functions can arise before gene duplication. Similarly, the “Duplication-Degeneration-Divergence” model highlights how ...

Gene duplication is very important for the evolution of species because it can facilitate the creation of new genes. Normally, changes to genes result in loss of function and so are weeded out by ...

The DPD model is based on a 'generalist' intermediate ... mutational effects dictate the likelihood and mechanism of gene duplication and divergence. We propose several factors that can affect ...

In 1970, Japanese-American biologist Susumu Ohno proposed that the main source of new genes is gene duplication. When the body’s genome has two copies of the same gene, one copy can continue ...

The authors propose that gene duplication is an important mechanism ... The woodrats could even serve as a model to understand why individual humans metabolize drugs differently.

Large and rare duplications and deletions in a chromosome ... meaning it can be inherited from just one parent -- of many gene mutations. The condition can lead to complications as severe as ...