Did you know that a large number of ... disease-related genes that were previously unknown. Current research aims to identify the functional mechanisms by which copy number variation cause diseases.

A) In a normal meiosis, chromosomes align precisely at the recombination site and crossovers do not change the number of genes in the ... human populations. Copy number variation (CNV) has ...

But measuring CNVs in cells from an individual can be tricky. For a number of years, researchers relied on fluorescently tagged microarray probes that attached to sections of genes; locations where ...

A significant advancement in knowledge of the link between cognition and genetics has been made thanks to a study led by ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate ... They analyzed all copy number variations in the 22q11.2 chromosome ...

Thanks to DNA mapping, these discoveries pave the way for a broader understanding of the ways in which genetic alterations ...