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Next, an equal volume of glutamine synthetase stop solution was added and the absorbance at 560 nm was determined. Absorbance values of the formed product glutamyl- γ-hydroxamate were converted ...
Glutamine-dependent amidotransferase (Gn-AT) catalyzes the transfer of the amido nitrogen of glutamine to an acceptor substrate to produce glutamate and an aminated product. Although most Gn-ATs ...
St. Jude Children’s Research Hospital scientists identified a previously unrecognized role for the amino acid glutamine in this process. In particular, the work reveals that modulating glutamine ...
The scientists suggest that if the reversal of glutamine metabolism does not occur ... oxidative stress causes impaired glutamine synthetase activity and accumulation of glutamate and ammonium ...
These findings result from fundamental biologic research to understand red blood cell metabolism ... the researchers found that the enzyme glutamine synthetase flips the script at later stages ...