The assembly of outer membrane proteins (OMPs) in Gram-negative bacteria is a critical process that ensures the integrity and functionality of the bacterial outer membrane. This membrane serves as ...

The outer membrane of Gram-negative bacteria is a complex structure that plays a crucial role in protecting the cell from environmental threats, including antibiotics. A key component of this ...

Second, the cell walls of gram-negative bacteria are surrounded by an outer membrane that has different properties than the inner membrane encased by the wall. This outer membrane is involved in ...

Scientists have uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum of antibiotics along ...

The Gram stain is a differential stain commonly used in the microbiology laboratory that differentiates bacteria on ... Gram-negative cell walls are more complex. They have a thin peptidoglycan layer ...

By analyzing E. coli protein levels, scientists found a surplus of membrane shuttle proteins that may play a role in antibiotic resistance.

A Cornell University-led collaboration has uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide ...

The new drug’s target is an enzyme called LpxC that is the second enzyme in the “Raetz pathway” and is essential to making the outer membrane lipid in gram-negative bacteria. Raetz joined Duke as the ...

MlaA, which in the cell is bound to another outer membrane protein called a porin, removes outer leaflet phospholipids and functions like a membrane vacuum cleaner that maintains the important ...

Bacteria are classified as either Gram-negative or Gram-positive based on their cell wall structure—Gram-negative bacteria have a thick layer of protection, making them difficult to kill. Most ...

Thus, formed colistin is active against MDR bacteria and CMS is an inactive prodrug. Colistin displaces divalent cations from the phosphate groups of membrane ... of MDR Gram-negative bacterial ...