This was an investigator-initiated, international, multicenter, prospective, randomized, open-label trial with blinded end-point assessment. The trial protocol was approved by the Dutch, Belgian ...

Randomized phase III trial of utidelone, a genetically engineered epothilone analog, in combination with capecitabine versus capecitabine alone for metastatic breast cancer patients with previous ...

Zanzalintinib (XL092) plus atezolizumab versus regorafenib in previously treated MSS/MSI-low metastatic colorectal cancer (mCRC): The randomized phase 3 STELLAR-303 study. This is an ASCO Meeting ...

The protocol for the LEAP study is available with the full text of this article at NEJM.org. Enrollment and Study Procedures Study enrollment took place from December 2006 to May 6, 2009.

Introduction Femoroacetabular impingement (FAI) syndrome is increasingly recognised as a cause of hip pain. As part of the design of a randomised controlled trial (RCT) of arthroscopic surgery for FAI ...

We conducted a randomized controlled trial to assess the feasibility of a 1:1:1 transfusion protocol and its effect on mortality and complications among patients with severe trauma. Methods: We ...