we generated recombinant, chromatinized cccDNA, allowing us to characterize its biophysical properties and to map ... HBV gene encoding protein X—the presence of nucleosomes on the viral genome ...
These patients usually harbor precore/core promoter mutations in the HBV genome that prevent or decrease the production of HBeAg. The prevalence and clinical significance of HBeAg-negative chronic ...
Occult HBV infection is defined by the existence of HBV DNA in serum, lymphoid cells (PBMC) and/or the liver and virus-genome replicative intermediates (i.e., covalently closed circular DNA ...
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