Biopharmaceuticals and biotherapeutics are medicines produced from living cells. But cells produce other proteins (called host cell proteins, or HCPs) that can contaminate the final therapeutic ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...

The endoplasmic reticulum (ER) is a crucial organelle present in all eukaryotic cells, including human cells. The ER plays a ...

A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

New phage are assembled before the host cell finally lyses and the phage progeny released into the surrounding environment to find new target cells. Phage receptor binding proteins are most frequently ...

Developed with antibodies from BioGenes GmbH, a global leader in host cell protein (HCP) assay development, the new kits enable rapid detection of HCPs from HEK293 cell lines, adding to Gyros ...

6 (2011). 2. Eberhardt et al. Host Immune Responses to a Viral Immune Modulating Protein: Immunogenicity of Viral Interleukin-10 in Rhesus Cytomegalovirus-Infected Rhesus Macaques. PLoSOne 7 (2012). I ...

To prevent bystander damage to host cells ... regulatory proteins. The new study led by Anna Ohradanova-Repic and colleagues from the Center for Pathophysiology, Infectiology and Immunology ...

Thus, changes in the proportion of NAD(P)H bound to proteins ... “The host cells may change their metabolism to resist the infection.” Shelby is an assistant editor for The Scientist. She earned her ...