Hypertonic saline refers to any saline solution with a concentration of sodium chloride (NaCl) higher than physiologic (0.9%). Commonly used preparations include 2%, 3%, 5%, 7%, and 23% NaCl.

To this note, we screened FDA approved reagents for their ability to enhance viral vector transduction of primary human airway epithelial cells and identified hypertonic saline as a candidate that ...