New therapeutic possibilities for various diseases are made possible via mRNA. The adaptability of in vitro transcribed (IVT) mRNA is largely due to its simpler cell-free manufacture, cell cycle ...

As the first step in many workflows, in vitro transcription (IVT) has quickly emerged as an essential part of successful mRNA therapeutic manufacturing processes, optimizing and accelerating ...

The importance of in vitro transcription as a component of the mRNA therapeutic manufacturing workflow has grown significantly in recent years. The in-process raw materials for synthetic mRNA ...

In vitro-transcribed (IVT) mRNA encoding therapeutic proteins, or viral antigens, had great potential for treating or preventing various diseases, but for years the body’s inflammatory response ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the ...

How does a COVID-19 mRNA vaccine work? COVID vaccines are now available. Some of the COVID-19 vaccines are mRNA vaccines, but what does this mean? mRNA vaccines are different from traditional ...

The rapid growth in IVT injections has resulted from the introduction of novel drug therapies. In 2004, only 2 agents were specifically approved by the United States Food and Drug Administration ...