Our cohort was divided in two groups: (i) in group A, real-time ultrasound-guided liver biopsy was performed by radiologists (241 patients; M/F, 135/106; median age 48 year (range 17-76).

Most metastatic deposits are solid and mainly hypoechoic relative to the background liver (Fig. 4). Many will exhibit a hypoechoic "halo" (Fig. 5). There is some controversy as to whether the halo ...