By expanding the intact samples in all directions, researchers can use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations.

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists ...

Not only could this help in identifying low-abundance targets, like PTMs, at the single-cell level, but it can also extend mass cytometry to studying smaller cells that traditional methods couldn’t ...

Mass cytometry (CyTOF®) is a powerful approach to characterize the immune composition of complex biological specimens and gain insights into immune correlates of disease. Successful large-scale CyTOF ...

Indiana University School of Medicine scientists have developed a powerful new imaging technique to study bone marrow in ...

For example, we are part of a single ... imaging technology with additional flow-cytometry parameters, we will be able to sort based on qualities such as nuclear translocation, or interacting cells.

The Hyperion Imaging System allows for simultaneous interrogation of 4-37 protein markers using a plate platform so that adherent cells can be imaged and analyzed without processing them into single ...