Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer ...

Researchers at Charles River have developed a series of small molecules that target the ATM kinase and have shown promise for the treatment of Huntington’s disease in preclinical studies In ...

Crohn's disease is an inflammatory bowel disease, which affects the lining ... monoclonal antibodies, and now oral small molecule. So really, targeted treatments on the immune system to control ...

Preclinical models are simplified tools that help researchers study these complex interactions in a controlled manner and prioritize relevant biochemical pathways when developing IBD therapies. These ...

Explore the complexities of Ulcerative Colitis, its causes, diagnostic methods, and breakthrough treatments for better management.

called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease ...

Three new IL-23 inhibitors have been approved for IBD, threatening Stelara’s long ... agents — such as biologics and advanced small molecules — earlier in the course of disease, there ...

In the guts of patients with inflammatory bowel disease (IBD), adenosine triphosphate (ATP) produced outside of cells leads to intestinal inflammation. Francisco Quintana, an immunologist and ...

Sabina Ali, MD Starting this summer, UCSF Benioff Children’s will be one of only a handful of children’s hospitals on the West Coast to offer intestinal ultrasound to children with inflammatory bowel ...