All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

This culminated in the introduction of a new class of anti-inflammatories — the COX2 selective inhibitors — with improved tolerance. There may be other forms of COX that could account for some ...

Celebrex works by blocking the COX-2 enzyme, which plays a crucial role in synthesizing prostaglandins that cause pain and ...

The mechanism of action of the ibuprofen, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Famotidine is a competitive inhibitor ...

The mechanism of action of indomethacin, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Use lowest effective dose for shortest ...

"Very lame and imperfect theories are sufficient to suggest useful experiments which serve to correct those theories and give birth to others more perfect. These, then occasion farther experiments ...