News
Insulators, also known as boundary elements, are DNA segments that work to prevent a gene from being influenced by the activation or repression of its neighbors.
Combined with their short nature (119–284 bp), these insulators seem to thus have important advantages over the 1.2-kb cHS4 element, which takes up valuable space in viral vectors and reduces titre.
A new study identifies molecular tools that exploit these properties to fine-tune transgenic gene expression through the use of site-specific integration and the gypsy insulator element.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results