Purpose. The efficacy and safety of and key clinical considerations for using U-500 insulin human regular in the treatment of high-dose insulin-treated patients in a wide variety of settings are ...
U-500 has prandial and basal time–action profile characteristics. d Basal insulin (glargine, detemir, or isophane [NPH]) may be substituted for bedtime U-500 insulin to adjust fasting blood ...
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