As the name suggests, an intervertebral disc is a cushion that lies between two vertebrae. It consists of two distinct components, nucleus pulposus and annulus fibrosus. The annulus fibrosus is a ...

The intervertebral discs between the spinal vertebrae comprise a gel-like core, the nucleus pulposus (NP), encased by a tough, fibrous outer ring. The NP’s high water content allows it to act ...

Your intervertebral discs have two layers. The nucleus pulposus is the softer, jelly-like inner layer. It acts as a shock absorber, dispersing forces when you move. The annulus fibrosis is the ...

Each vertebra is separated by a cushion of intervertebral discs. These discs consist of an inner core called the nucleus pulposus. They’re held intact by a strong outer ring of ligament fibers ...

He explains that this column contains of 23 segments, called intervertebral discs ... the softer inner material of the disc, known as the nucleus pulposus." When that outer ring becomes damaged ...

The focus of this research revolved around nucleus pulposus cells (NPCs), pivotal in IDD, and how oxygen levels and the HIF1A gene could influence them. Employing advanced RNA sequencing (RNA-seq ...

Lumbar disc herniation occurs when the nucleus pulposus of an intervertebral disc protrudes through a tear in the surrounding annulus fibrosus. Symptoms include pain in the back, pain in the leg ...

Lumbar disc herniation occurs when the nucleus pulposus of an intervertebral disc protrudes through a tear in the surrounding annulus fibrosus. Symptoms include pain in the back, pain in the leg ...

Finally, nociceptive nerve fibers that are present in the annulus and nucleus pulposus become sensitized ... of — degeneration of the intervertebral disk. Such degeneration leads to pain and ...