Scientist Sarallah Rezazadeh from the Icahn School of Medicine explores the molecular mechanisms behind adult stem cells as ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

Blood stem cells and intestinal stem cells for example constantly produce new progeny. In contrast to this, muscle stem cells are normally quiescent and activate only if they receive a signal of ...

More information: Jaakko Mattila et al, Stem cell mTOR signaling directs region-specific cell fate decisions during ...

Impact of the stem cell niche on aging: we study the communication between stem cells and their niche (e.g. neighbor cells, ECM) in multiple tissues including the intestine, mammary, skeletal muscle, ...